DUO
- Stage boundary
- No direct role is recorded for Acquire, Harmonize.
- Known limitation
- Ontology matching cannot resolve jurisdiction, contract, consent nuance, expiry, or downstream duties without authoritative policy and human governance.
Decision support
Place up to three profiles side by side. Focus on architectural role, evidence, and the first limitation to test—not on finding a single all-purpose standard.
Working set
1 of 3 selected
Decision lens
The useful question is not “Which standard wins?” It is “Which job must this part of the architecture perform, and what remains uncovered?”
Decide whether you need guidance, a domain payload, exchange, semantics, governance, or a reusable release.
Use the matrix to see where each profile has a direct role. A filled cell is coverage, not a quality score.
Read what each option leaves unresolved before judging maturity, confidence, or implementation fit.
Three-part assessment
Read left to right. Lifecycle reach comes first; maturity remains an editorial roll-up, not certification.
01 · Lifecycle reach
Coverage shows a recorded role at that readiness stage. It does not imply end-to-end implementation.
| Profile | Plan | Acquire | Harmonize | Exchange | Learn + reuse |
|---|---|---|---|---|---|
| DUOOntology / data model | GA4GH Data Use Ontology has a direct role in Plan. | GA4GH Data Use Ontology has no direct role recorded in Acquire. | GA4GH Data Use Ontology has no direct role recorded in Harmonize. | GA4GH Data Use Ontology has a direct role in Exchange. | GA4GH Data Use Ontology has a direct role in Learn + reuse. |
02 · Boundaries
These are design boundaries, not faults. Use them to identify the companion layers your architecture still needs.
03 · Detailed assessment
Use the source, status, and limitation together. A higher maturity label does not erase a scope mismatch.
| Assessment | DUOGA4GH Data Use Ontology |
|---|---|
| Purpose & coverage | Standardized biomedical data-use permission terms for matching controlled-access datasets to research purposes. Best fitConsent-aware discovery, data access review, and machine-readable permitted-use conditions in genomics and health research. |
| Readiness stages | PlanExchangeLearn + reuse |
| AI-ready contribution | Helps agents screen permitted uses, but does not establish lawful access, fairness, privacy protection, or security by itself. |
| First limitation to test | Ontology matching cannot resolve jurisdiction, contract, consent nuance, expiry, or downstream duties without authoritative policy and human governance. |
| Evidence | E1 + E2 High confidence Formal statusGA4GH maintained production product ReviewSource-checked |
| Maturity | Established Production-status product with named implementations |
| Sources & links | GA4GH Data Use Ontology (opens in a new tab)Read full profile |